Does Xanax make you lose weight?
Xanax (alprazolam) is a drug used essentially for the intense administration of tension issue – especially panic issues. When administered, Xanax crosses the blood-brain barrier and tweaks the enactment of GABAA receptor alpha-1 subunits.
Besides, in light of the fact that Xanax is a quick acting drug, many believe Xanax to be one of the best medicines for panic diseases. Albeit numerous people see Xanax as exceptionally viable in overseeing nervousness issue, some forthcoming clients might be worried about the potential reaction of weight change.
Xanax (Alprazolam) Weight Gain vs. Weight Loss
Information from randomized controlled trails show that Xanax is probably not going to cause clinically important weight gain (described as 7% body weight increment from baseline). In any case, consequences of different 8-week randomized controlled trials demonstrate that progressing Xanax administration (at moderate dosages) may cause slight weight reduction in a subset of recipients.
Understand that although clinical trials report average incidence rates of side effects (e.g. weight change), your experience might be inconsistent with the research. In other words, there’s a chance that you could be an “outlier” or abnormal responder such that you end up gaining or losing significantly more weight than other Xanax users.
Potential reasons somebody may encounter weight change while taking Xanax include: hunger change; body structure change; energy level fluctuation; as well as move in metabolic rate. Also, it's important to underscore that the hidden cause(s) of weight change among Xanax clients could be dependent upon significant interindividual variety; what causes weight change for one client – probably won't clarify the weight change of another.
Does Xanax cause weight gain or weight loss?
Acute & low-dose Xanax:
Weight gain. Multiple studies suggest that acute Xanax administration at low doses (0.75 mg)
significantly increases caloric intakes ofwomen with PMS and healthy males. In women with PMS, caloric intakes increased by 9% to 26% and were most significant among women characterized as “restrained eaters” (women who typically restrain themselves around food). In healthy males, caloric intakes increased by ~975 kcal per day while using Xanax.
Longer-term & high-dose Xanax:Weight loss. Two randomized controlled trials suggest that Xanax is likely to induce modest weight loss when used daily for a longer-term (8-weeks) at clinically-relevant doses (5-6 mg). In one of the studies, weight loss was associated with appetite loss, whereas in the other, weight loss occurred despite increased appetite.
Factors that influence may Xanax-mediated weight change
Variables that might impact weight change (and its significance) while using Xanax include: Xanax dose; duration of treatment; and use of other substances. Things like your baseline weight; previous substance use; lifestyle; and genetics – might also influence weight change on Xanax.
If Xanax-mediated physiologic changes and/or side effects stemming from CNS suppression is culpable for your weight change – then high doses may be more likely to amplify this effect. Because low doses of Xanax won’t affect neurophysiology as much as high doses – weight change should be less likely to occur and less significant (if it occurs) compared to high doses.
Duration of use
If you’ve experienced weight change from Xanax, the total duration of your treatment could’ve played a role. In some cases, short-term Xanax use can cause transient weight gain because the user’s physiology hasn’t fully adapted itself to the medication’s presence. With longer-term use, weight may revert back to baseline as the body becomes better adjusted to Xanax.
Furthermore, some individuals may experience a small amount of weight change (gain or loss) over the short-term – followed by weight stabilization (i.e. no further change) with longer-term treatment. On the other hand, some individuals may not experience any significant weight change over the short-term, but might notice gradual changes over the long-term (possibly due to dosage increases and/or muscle loss).
Lifestyle & genetics
A Xanax user’s lifestyle and genetics could impact the amount of weight change experienced during treatment. Individuals who meticulously track calorie intake and make a concerted effort to regularly exercise – might experience zero weight change while taking Xanax because they’ve maintained the same energy intake and expenditure (as pre-treatment).
In fact, deliberate restriction of calories and/or increased exercise could lead to weight loss from Xanax. On the other hand, persons who never track calories or exercise might end up experiencing unwanted weight gain while taking Xanax because they unknowingly end up consuming more calories during treatment or exercise less (compared to pre-treatment).
It very well may be utilized securely and adequately when recommended properly, after thoroughly assessing the dangers and advantages of treatment. Symptoms are normal, yet regularly ignored by patients, given its quick beginning of helpful activity and one of its strengthening properties. The common complaints detailed with a variety of patients treated with alprazolam includes sedation, weakness, ataxia, amnesia, slurred speech, poor fixation, excessive touchiness, and irritability.